anti- XBP1 antibody

PRODUCT INFORMATION

Product Name

XBP1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

X-box-binding protein 1(XBP1), also named as TREB5, is a 261 amino acid protein, which contains one bZIP domain and belongs to the bZIP family. XBP1 localizes in the nucleus and as a transcription factor is essential for hepatocyte growth, the differentiation of plasma cells, the immunoglobulin secretion, and the unfolded protein response. XBP1 has an association with major affective disorder. The molecular weight of protein generated from the spliced XBP1 mRNA is 54 kDa and protein generated from unspliced Xbp1 mRNA is 33 kDa.

IMMUNOGEN INFORMATION

Immunogen

X-box binding protein 1

Synonyms

TREB5, X box binding protein 1, XBP 1, XBP1, XBP2

Observed MW

29 kDa

APPLICATION

Tested Application

ELISA, WB,IHC

Recommended Dilution

WB: 1:200-1:1000; IHC: 1:50-1:500

UNIPROT INFORMATION

UniProt ID

P17861

Immunohistochemistry of paraffin-embedded human liver cancer tissue slide using FNab09537(XBP1 Antibody) at dilution of 1:100.

rat spleen tissue were subjected to SDS PAGE followed by western blot with FNab09537(XBP1 Antibody) at dilution of 1:300