anti- XRCC4 antibody

PRODUCT INFORMATION

Product Name

XRCC4 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

The protein encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand breaks. This protein plays a role in both non-homologous end joining and the completion of V(D)J recombination. Mutations in this gene can cause short stature, microcephaly, and endocrine dysfunction (SSMED). Alternative splicing generates several transcript variants.

IMMUNOGEN INFORMATION

Immunogen

X-ray repair complementing defective repair in Chinese hamster cells 4

Synonyms

DNA repair protein XRCC4, XRCC4

Observed MW

45 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:10 - 1:100

UNIPROT INFORMATION

UniProt ID

Q13426

Immunohistochemistry of paraffin-embedded human breast cancer using FNab09554(XRCC4 antibody) at dilution of 1:100

Immunofluorescence analysis of U2OS cells using FNab09554(XRCC4 antibody) at dilution of 1:100. Blue: DAPI for nuclear staining.

K-562 cells were subjected to SDS PAGE followed by western blot with FNab09554(XRCC4 antibody) at dilution of 1:1000