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FNab09780

anti- CD45 antibody

anti- CD45 antibody

$280.00 USD
$280.00 USD
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Size
Host
Clonality

Discover the fascinating world of cellular identity and immunology with our Anti-CD45 Antibody, now available in a 100µg size. CD45, also known as leukocyte common antigen (LCA), is a pivotal cell surface protein expressed on all nucleated hematopoietic cells, making it a fundamental marker for identifying leukocytes.

This monoclonal antibody offers high specificity and sensitivity, making it an essential tool for researchers investigating hematopoietic cell populations, immune cell activation, and immune responses. With 100µg of this antibody, you'll have a substantial supply for multiple experiments, ensuring the uninterrupted progression of your research.

Explore the intricate mechanisms by which CD45 regulates immune cell signaling, activation, and its role in immune-related disorders. Investigate the molecular intricacies of CD45-mediated processes, contributing to our understanding of hematopoiesis and potential therapeutic interventions.

Product Name

CD45 antibody

Size

100µg

Form

liquid

Purification

Protein A+G purification

Purity

≥95% as determined by SDS-PAGE

Host

Mouse

Clonality

monoclonal

Isotype

IgG2a

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

CD45, also known as leukocyte common antigen(LCA), B220, and T200, is a 180-240 kD single chain type I membrane glycoprotein. It is a tyrosine phosphatase expressed on the plasma membrane of all hematopoietic cells, except erythrocytes and platelets. CD45 is a signaling molecule that regulates a variety of cellular processes including cell growth, differentiation, cell cycle, and oncogenic transformation.

IMMUNOGEN INFORMATION

Immunogen

protein tyrosine phosphatase, receptor type, C

Synonyms

B220, CD45, CD45R, GP180, L CA, LCA, Leukocyte common antigen, LY5, PTPRC, RPTPC, T200

Observed MW

180-220 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, FC

Recommended Dilution

WB: 1:1000-1:10000; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

P08575

IMAGES

 

Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using FNab09780(CD45 Antibody) at dilution of 1:300. heat mediated antigen retrieved with Tris-EDTA buffer(pH9).
Raji cells were subjected to SDS PAGE followed by western blot with FNab09780(CD45 Antibody) at dilution of 1:1000

 

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