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FNab09800

anti- Vinculin antibody

anti- Vinculin antibody

$280.00 USD
$280.00 USD
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Size
Host
Clonality

Product Name

Vinculin antibody

Size

100µg

Form

liquid

Purification

Protein A+G purification

Purity

≥95% as determined by SDS-PAGE

Host

Mouse

Clonality

monoclonal

Isotype

IgG1

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Vinculin belongs to the vinculin/alpha-catenin family. It is an actin filament(F-actin)-binding protein which involved in cell-matrix adhesion and cell-cell adhesion. Vinculin regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. It may also play important roles in cell morphology and locomotion. Vinculin is a 117-kDa, 1,066-amino-acid protein which is ubiquitously expressed. Its splice variant, metavinculin(124 kDa), is muscle-specific.

IMMUNOGEN INFORMATION

Immunogen

vinculin

Synonyms

CMD1W, Metavinculin, MVCL, VCL, Vinculin

Observed MW

124 kDa

APPLICATION

Tested Application

ELISA, FC, IF, IHC, WB

Recommended Dilution

WB: 1:2000-1:20000; IHC: 1:50-1:500; IF: 1:50-1:500

UNIPROT INFORMATION

UniProt ID

P18206

IMAGES

 

Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using FNab09800(Vinculin Antibody) at dilution of 1:200
Immunofluorescent analysis of ( 4% PFA) fixed Hela cells using FNab09800 (vinculin antibody) at dilution of 1:50 and FITC-conjugated Goat Anti-Mouse IgG(H+L)
hela lysates were subjected to SDS PAGE followed by western blot with FNab09800(Vinculin Antibody) at dilution of 1:5000

 

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