anti- C-FOS antibody

Uncover the intricate world of gene expression and transcriptional regulation with our Anti-C-FOS Antibody, available in a 100µg size. This high-quality polyclonal antibody, hosted in rabbit, is your essential tool for studying the C-FOS protein, a key player in cellular responses to stimuli.

Engineered for precision and versatility, this antibody ensures exceptional sensitivity in applications such as western blotting, immunofluorescence, and immunoprecipitation. Whether you're investigating C-FOS's role in signal transduction pathways, cellular stress responses, or its interactions with other transcription factors, this antibody enhances your research capabilities.

C-FOS is a well-known proto-oncogene and a component of the AP-1 transcription factor complex. It is involved in a wide array of cellular processes, including growth, differentiation, and response to extracellular signals. Understanding C-FOS's functions and its regulatory networks is crucial for deciphering its contributions to both normal physiology and pathological conditions.

With our Anti-C-FOS Antibody, you can delve into C-FOS's functionality, explore its impact on gene expression, and potentially advance research in cancer biology, cellular stress responses, and gene regulation. Elevate your research in signal transduction and transcriptional control with this precision antibody.

Product Name

C-FOS antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

c-FOS, also named as Proto-oncogene c-Fos and G0/G1 switch regulatory protein 7, is a 380 amino acid protein, which contains 1 bZIP(basic-leucine zipper) domain and belongs to the bZIP family. FOS is expressed at very low levels in quiescent cells. When cells are stimulated to reenter growth, FOS undergo 2 waves of expression, the first one peaks 7.5 minutes following FBS induction. At this stage, the FOS protein is localized endoplasmic reticulum. The second wave of expression occurs at about 20 minutes after induction and peaks at 1 hour. At this stage, the FOS protein becomes nuclear. The calculated molecular weight of FOS is 40 kDa, but Phosphorylated FOS protein is about 60-65 kDa.

IMMUNOGEN INFORMATION

Immunogen

Proto oncogene c Fos

Synonyms

AP 1, C FOS, Cellular oncogene fos, c-FOS, FOS, G0S7, Proto oncogene c Fos

Observed MW

65 kDa

APPLICATION

Tested Application

ELISA, IF, IHC, WB

Recommended Dilution

WB: 1:500-1:2000; IHC: 1:200-1:800; IF: 1:50-1:500

UNIPROT INFORMATION

UniProt ID

P01100

IMAGES