anti- P Glycoprotein antibody

Product Name

P Glycoprotein antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

ABCB1(also known as P-gp/ P-glycoprotein, MDR1/multidrug-resistance 1) is a plasma membrane protein first discovered in multidrug resistant tumor cells. ABCB1 can extrude a large number of medically relevant compounds from cells and causes drug resistance. ABCB1 is expressed in a variety of human cancers as well as normal tissues including brain, and placenta. Overexpression of ABCB1 correlates with a negative prognosis in several types of cancer.

IMMUNOGEN INFORMATION

Immunogen

ABCB1

Synonyms

ABCB1, CD243, GP170, MDR1, Multidrug resistance protein 1, P glycoprotein 1

Observed MW

142 kDa

APPLICATION

Tested Application

ELISA, WB, IP, IHC

Recommended Dilution

WB: 1:200-1:1000; IP: 1:200-1:1000; IHC: 1:50-1:500

UNIPROT INFORMATION

UniProt ID

P08183

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