anti- FHIT antibody

Delve into the intricate world of Fragile Histidine Triad Protein (FHIT) with our Anti-FHIT Antibody, available in a 100µg vial. FHIT is a tumor suppressor protein involved in the regulation of DNA damage and cell growth. This highly specific antibody empowers researchers to explore the multifaceted role of FHIT in cancer biology and cellular integrity with precision and reliability.

Key Features:

• Exceptional Specificity: Our Anti-FHIT Antibody is rigorously tested to ensure it accurately targets FHIT, reducing the risk of cross-reactivity.
• Versatile Applications: Perfect for a wide range of experimental techniques, including immunohistochemistry, Western blotting, and immunoprecipitation.
• Ample Quantity: With 100µg, you have a generous supply for multiple experiments.
• Top-Tier Quality: Manufactured to the highest industry standards, ensuring consistent and reproducible results.
• Advance Your Research: Whether you're studying cancer biology, DNA damage, or cell growth regulation, our Anti-FHIT Antibody is your key to unlocking new knowledge.

Uncover the intricate role of FHIT in complex biological processes and elevate your research with our Anti-FHIT Antibody.

Product Name

FHIT antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

This gene, a member of the histidine triad gene family, encodes a diadenosine 5', 5'''-P1, P3-triphosphate hydrolase involved in purine metabolism. The gene encompasses the common fragile site FRA3B on chromosome 3, where carcinogen-induced damage can lead to translocations and aberrant transcripts of this gene. In fact, aberrant transcripts from this gene have been found in about half of all esophageal, stomach, and colon carcinomas. Alternatively spliced transcript variants have been found for this gene.

IMMUNOGEN INFORMATION

Immunogen

FHIT

Synonyms

AP3Aase, FRA3B

Observed MW

35 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

UNIPROT INFORMATION

UniProt ID

P49789

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