anti- Cytochrome c antibody

Our Anti-Cytochrome c Antibody, available in a 100µg size, is a valuable tool for researchers investigating the expression and functions of cytochrome c, a critical component of the mitochondrial electron transport chain.

Cytochrome c plays a central role in the process of oxidative phosphorylation, where it shuttles electrons between respiratory complexes, ultimately contributing to ATP production. Understanding the regulation and localization of cytochrome c is essential for unraveling its contributions to cellular bioenergetics and apoptosis.

This antibody has been meticulously validated for specificity and sensitivity, ensuring robust and reproducible results in your experiments. Whether you're conducting immunohistochemistry, immunofluorescence, or Western blotting, its compact size offers versatility in applications.

Trust in the quality of our Anti-Cytochrome c Antibody to accelerate your research and deepen your understanding of cytochrome c's role in mitochondrial function and cellular signaling pathways, with potential implications in cell biology and disease mechanisms.

Product Name

Cytochrome c antibody

Size

100µg

Form

liquid

Purification

Protein A+G purification

Purity

≥95% as determined by SDS-PAGE

Host

Mouse

Clonality

monoclonal

Isotype

IgG2a

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Cytochrome c is a 12-15 kDa electron transporting protein located in the inner mitochondrial membrane. Upon apoptotic stimulation, cytochrome c can be released from mitochondria into cytoplasm, resulting in caspase-3 activation and apoptosis. Measurement of cytochrome c release from the mitochondria is useful for detection of the onset of apoptosis in cells. In addition, cytochrome c can also leave cells and be detectable in extra-cellular medium of apoptotic cells and serum of cancer patients. The level of serum cytochrome c may serve as a prognostic maker during cancer therapy.

IMMUNOGEN INFORMATION

Immunogen

Cytochrome c

Synonyms

CYC, CYCS, Cytochrome c, cytochrome c, somatic, HCS, THC4

Observed MW

12 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:5000-1:30000; IHC: 1:100-1:1000

UNIPROT INFORMATION

UniProt ID

P99999

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