anti- CD8A antibody

Delve into the intricate world of T-cell immunology and cytotoxic T lymphocytes with our Anti-CD8A Antibody, available in a 100µg size. CD8A, a crucial subunit of the CD8 complex, is a key surface marker on cytotoxic T cells, and this highly specific monoclonal antibody offers precise targeting for your research needs.

Whether you're involved in flow cytometry, immunohistochemistry, or functional assays, this antibody provides consistent and dependable results. It is an indispensable tool for advancing your understanding of CD8A-mediated immune responses and its implications in infection and cancer immunotherapy.

Trust in the quality and performance of our Anti-CD8A Antibody to drive your research forward and contribute to a better understanding of T-cell biology and immune cell function.

Product Name

CD8A antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene.

IMMUNOGEN INFORMATION

Immunogen

CD8A

Synonyms

CD8, Leu2, MAL, p32

Observed MW

30 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

UNIPROT INFORMATION

UniProt ID

P01732

IMAGES