anti- CXCR3 antibody

Our Anti-CXCR3 Antibody, available in a 100µg size, is an essential tool for researchers studying CXCR3, a chemokine receptor with critical roles in immune cell trafficking, inflammation, and cancer biology.

CXCR3, also known as C-X-C chemokine receptor type 3, is a key player in various physiological and pathological processes, making it a central focus of research in diverse fields. With our antibody, you can confidently investigate the functions and interactions of CXCR3, gaining insights into its significance in cellular biology.

We have rigorously validated the specificity and sensitivity of this antibody to ensure accurate and reproducible results in your experiments. Its compact size allows for versatility in applications, whether you're conducting flow cytometry, immunohistochemistry, or in vivo studies. Trust in the quality of our Anti-CXCR3 Antibody to advance your scientific investigations and contribute to a deeper understanding of chemokine receptor signaling.

Product Name

CXCR3 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

This gene encodes a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-g), CXCL10/IP10 (interferon-g-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell a-chemoattractant). Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the isoforms (CXCR3-B) shows high affinity binding to chemokine, CXCL4/PF4 (PMID:12782716).

IMMUNOGEN INFORMATION

Immunogen

CXCR3

Synonyms

CD182, CD183, CKR-L2, CMKAR3, GPR9, IP10-R, Mig-R, MigR

Observed MW

45 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:100

UNIPROT INFORMATION

UniProt ID

P49682

IMAGES