anti- Collagen Type I antibody

Embark on a journey into the world of structural support and tissue resilience with our Anti-Collagen Type I Antibody, available in a convenient 100µg size. Collagen Type I is the most abundant collagen in the human body, forming the foundation of skin, bones, and connective tissues. This high-quality antibody is your essential tool for unraveling the complexities of collagen I in various physiological processes.

Our antibody is meticulously designed and rigorously validated to ensure specificity and sensitivity, enabling accurate and reproducible results in your experiments. Whether you're investigating tissue development, scar formation, or the role of collagen I in disease, this antibody will be your reliable research companion.

The 100µg size provides an ample supply of antibody to support your experiments without the need for frequent reordering. Choose our Anti-Collagen Type I Antibody to advance your scientific endeavors and contribute to a deeper understanding of collagen I's pivotal role in tissue biology.

Product Name

Collagen Type I antibody

Size

100µg

Form

liquid

Purification

protein A+G purified

Purity

≥95% as determined by SDS-PAGE

Host

Mouse

Clonality

monoclonal

Isotype

IgG1

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

This gene encodes the pro-alpha2 chain of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIB, recessive Ehlers-Danlos syndrome Classical type, idiopathic osteoporosis, and atypical Marfan syndrome. Symptoms associated with mutations in this gene, however, tend to be less severe than mutations in the gene for the alpha1 chain of type I collagen (COL1A1) reflecting the different role of alpha2 chains in matrix integrity. Three transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene.

IMMUNOGEN INFORMATION

Immunogen

collagen, type I, alpha 2

Synonyms

Alpha 2 type I collagen, COL1A2, Collagen alpha 2(I) chain, Collagen Type I, collagen, type I, alpha 2, OI4

APPLICATION

Tested Application

ELISA, IHC

Recommended Dilution

IHC: 1:200 - 1:1000

UNIPROT INFORMATION

UniProt ID

P08123

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