anti- CD206 antibody

Embark on a journey to investigate the roles of CD206 in macrophage biology with our Anti-CD206 Antibody, now available in a 100µg size. CD206, also known as mannose receptor C type 1 (MRC1), is a cell surface receptor predominantly expressed on macrophages, where it plays a critical role in antigen uptake and immune regulation.

Our meticulously developed monoclonal antibody ensures exceptional specificity and sensitivity, making it the ideal choice for various applications, including flow cytometry, Western blotting, and immunohistochemistry. It provides the precision and reliability needed for accurate results in your CD206-related research.

With 100µg at your disposal, you have a substantial supply for multiple experiments, ensuring the continuity of your research without frequent reordering.

Uncover the multifaceted functions of CD206 in macrophage-mediated immune responses and its implications in inflammation and tissue repair. With our Anti-CD206 Antibody, you can confidently advance your research and contribute to advancements in immunology and immunotherapy.

Product Name

CD206 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

CD206, also named as MMR, CLEC13D and MRC1, is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. CD206 has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment. CD206 is a 170 kDa transmembrane protein which contains 5 domains: an amino-terminal cysteine-rich region, a fibronectin type II repeat, a series of eight tandem lectin-like carbohydrate recognition domains(responsible for the recognition of mannose and fucose), a transmembrane domain, and an intracellular carboxy-terminal tail. It is expressed on most tissue macrophages, in vitro derived dendritic cells, lymphatic and sinusoidal endothelia.

IMMUNOGEN INFORMATION

Immunogen

mannose receptor, C type 1

Synonyms

CD206, CLEC13D, Macrophage mannose receptor 1, Mannose receptor, mannose receptor, C type 1, MMR, MRC1

Observed MW

166 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF

Recommended Dilution

WB: 1:200-1:2000; IHC: 1:50-1:200; IF: 1:50-1:200

UNIPROT INFORMATION

UniProt ID

P22897

IMAGES