anti- CTNNB1 antibody

The anti-CTNNB1 antibody, available in a 100µg size, is a crucial tool for researchers exploring the functions of Catenin beta-1 (CTNNB1) in various cellular processes, particularly its roles in Wnt signaling, cell adhesion, and gene transcription.

This polyclonal antibody is meticulously designed to target CTNNB1 with exceptional specificity and sensitivity, making it suitable for various applications, including Western blotting, immunohistochemistry, and chromatin immunoprecipitation (ChIP).

Our anti-CTNNB1 antibody is sourced from high-quality materials and undergoes rigorous validation to ensure reliable and reproducible results. It is a trusted choice for researchers investigating the molecular mechanisms of Wnt signaling, cancer biology, and embryonic development.

The 100µg size of this antibody provides researchers with an ample supply for multiple experiments, and it is compatible with various sample types, including cell lysates and tissue sections. Whether studying cell signaling, tumorigenesis, or stem cell biology, this antibody is an invaluable resource for your research.

Product Name

CTNNB1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants.

IMMUNOGEN INFORMATION

Immunogen

catenin(cadherin-associated protein), beta 1, 88kDa

Synonyms

b cat, Beta catenin, beta-Catenin, Catenin beta 1, CTNNB, CTNNB1, PRO2286, β catenin, β-catenin

Observed MW

90 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500-1:2000; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

P35222

IMAGES

 

Immunohistochemistry of paraffin-embedded human liver cancer tissue slide using FNab09998(CTNNB1 Antibody) at dilution of 1:200

mouse heart tissue were subjected to SDS PAGE followed by western blot with FNab09998(CTNNB1 antibody) at dilution of 1:1000