anti- CD3 epsilon antibody

Embark on a journey into the world of T-cell signaling with our Anti-CD3 Epsilon Antibody, now available in a 100µg size. CD3 Epsilon, a vital component of the T-cell receptor (TCR) complex, is essential for T-cell activation and immune response regulation.

Our monoclonal antibody delivers precise and reliable results in various research applications, including Western blotting and flow cytometry. With 100µg of this antibody at your disposal, you have an ample supply for multiple experiments, ensuring the continuity of your research.

Explore the multifaceted functions of CD3 Epsilon in T-cell signaling, shedding light on critical mechanisms governing immune cell activation, cytokine production, and immune response modulation. Our Anti-CD3 Epsilon Antibody empowers you to confidently advance your investigations, contributing to breakthroughs in immunology and immunotherapy research.

Whether you're a seasoned immunologist or new to the field of T-cell signaling, this antibody provides the precision, reliability, and quantity you need to propel your research forward. Navigate the intricacies of immune cell activation with this indispensable research tool.

Product Name

CD3 epsilon antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

CD3 is a complex of proteins that directly associates with the T cell receptor (TCR). The TCR/CD3 complex of T-lymphocytes consists of either a TCR alpha/beta or TCR gamma/delta heterodimer coexpressed at the cell surface with the invariant subunits of CD3 labeled gamma, delta, epsilon, zeta, and eta. The TCR recognizes antigens bound to major histocompatibility complex (MHC) molecules. TCR-mediated peptide-MHC recognition is transmitted to the CD3 complex, leading to the intracellular signal transduction. CD3 is considered to be a pan-T cell marker for detection of normal and neoplastic T cells.

IMMUNOGEN INFORMATION

Immunogen

CD3e molecule, epsilon (CD3-TCR complex)

Synonyms

CD3, CD3 epsilon, CD3E, CD3-epsilon, T3E, TCRE

Observed MW

23-25 kDa

APPLICATION

Tested Application

ELISA, WB

Recommended Dilution

WB: 1:500 - 1:2000

UNIPROT INFORMATION

UniProt ID

P07766

IMAGES

various lysates were subjected to SDS PAGE followed by western blot with FNab10016( CD3E Antibody) at dilution of 1:1000