anti- Endoglin/CD105 antibody

Dive into the world of vascular biology with our anti-Endoglin/CD105 antibody. Endoglin, also known as CD105, is a key player in endothelial cell function and vascular development. This 100µg antibody provides you with a valuable tool to investigate Endoglin's functions and interactions.

Study how Endoglin contributes to angiogenesis, endothelial cell activation, and its significance in cardiovascular health. Whether you're conducting research, diagnostics, or drug development, our antibody is designed for flexibility and ease of use, ensuring precise and reliable results in various applications.

Count on our dedication to quality and accuracy as you decipher the roles of Endoglin/CD105 in vascular biology and its impact on human health

Product Name

Endoglin/CD105 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

IMMUNOGEN INFORMATION

Immunogen

endoglin

Synonyms

CD105, END, Endoglin, ENG, FLJ41744, HHT1, ORW, ORW1

Observed MW

50 kDa, 67 kDa

APPLICATION

Tested Application

ELISA, WB

Recommended Dilution

WB: 1:200-1:2000

UNIPROT INFORMATION

UniProt ID

P17813

IMAGES

MCF-7 cells were subjected to SDS PAGE followed by western blot with FNab10035(ENG antibody) at dilution of 1:1000