anti- MGMT antibody

Product Name

MGMT antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Involved in the cellular defense against the biological effects of O6-methylguanine(O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.

IMMUNOGEN INFORMATION

Immunogen

O-6-methylguanine-DNA methyltransferase

Synonyms

MGMT

Observed MW

22 kDa

APPLICATION

Tested Application

ELISA, IHC

Recommended Dilution

IHC: 1:50 - 1:500

UNIPROT INFORMATION

UniProt ID

P16455

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