anti- CASP7 antibody

Our Anti-CASP7 Antibody is an invaluable tool for researchers exploring apoptosis, a fundamental cellular process with implications in various diseases, including cancer. Caspase-7 (CASP7) is a critical effector caspase involved in executing apoptosis by cleaving key cellular substrates.

This antibody is meticulously designed to selectively recognize CASP7, ensuring the specificity of your experiments. It is compatible with various applications, including Western blotting and immunofluorescence, offering versatility in your research.

With the 100µg vial size, you'll have an ample supply of this high-quality antibody for multiple experiments, ensuring cost-effectiveness and consistent results. Dive into the intricate world of apoptosis and CASP7's pivotal role in orchestrating cell death with confidence, knowing you have a trusted research partner.

Product Name

CASP7 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of the encoded protein is cleaved by caspase 3 and 10, is activated upon cell death stimuli and induces apoptosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

IMMUNOGEN INFORMATION

Immunogen

caspase-7

Synonyms

CASP-7, CMH-1, ICE-LAP3, LICE2, MCH3

Observed MW

37kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:100

UNIPROT INFORMATION

UniProt ID

P55210

IMAGES

Immunohistochemistry of paraffin-embedded rat heart using FNab10124(CASP7 antibody) at dilution of 1:100

Immunofluorescent analysis of HeLa cells using FNab10124( CASP7 Antibody).

293T cells were subjected to SDS PAGE followed by western blot with FNab10124( CASP7 Antibody) at dilution of 1:1000