anti- c-MYC antibody

Investigate the pivotal functions of c-MYC with our Anti-c-MYC Antibody, available in a 100µg size. This high-quality antibody is your versatile tool for studying c-MYC, a transcription factor with far-reaching implications in cell proliferation, differentiation, and apoptosis.

Engineered for precision and reliability, this antibody ensures exceptional sensitivity in applications such as western blotting, chromatin immunoprecipitation, and immunofluorescence. Whether you're unraveling c-MYC's role in oncogenesis, gene regulation, or its interactions with other transcriptional regulators, this antibody enhances your research capabilities.

c-MYC, a proto-oncogene, plays a pivotal role in controlling gene expression and cell fate decisions. Dysregulation of c-MYC is a hallmark of many cancers, making it a target of intense research interest.

With our Anti-c-MYC Antibody, you can delve into c-MYC's functionality, explore its impact on gene regulation, and potentially advance research in cancer biology and transcriptional control. Elevate your research in understanding the roles of c-MYC in cellular processes with this precision antibody.

Product Name

c-MYC antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

MYC contains one basic helix-loop-helix(bHLH) domain. This protein is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. It seems to activate the transcription of growth-related genes. It binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. This antibody is a rabbit polyclonal antibody raised against recombinant protein of human MYC.The 50kDa band recognized by antibody is the native form of MYC, while the other bands, between 60-70kDa, are the phosphorylated form of MYC [PMID: 12189186]

IMMUNOGEN INFORMATION

Immunogen

v-myc myelocytomatosis viral oncogene homolog(avian)

Synonyms

BHLHe39, c Myc, c-Myc, MRTL, MYC, Myc proto oncogene protein, Proto oncogene c Myc, Transcription factor p64

Observed MW

50-60 kDa

APPLICATION

Tested Application

ELISA, WB

Recommended Dilution

WB: 1:500-1:2000

UNIPROT INFORMATION

UniProt ID

P01106

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