anti- ABCC6 antibody

Chart new pathways in cellular transport with our Anti-ABCC6 Antibody, meticulously developed for your research needs. This antibody, sourced from rabbit hosts and featuring a polyclonal clonality, is available in a generous 100µg size, providing you with ample resources for your experiments.

ABCC6, a critical member of the ATP-binding cassette (ABC) transporter family, is renowned for its role in transmembrane transport and cellular detoxification. Our antibody is tailored to specifically target ABCC6 with remarkable precision and sensitivity. Extensively validated, it guarantees consistent and trustworthy results, empowering you to explore cellular transport dynamics with confidence.

Utilizing state-of-the-art techniques, our antibody offers versatility for a wide range of applications, including Western blotting, immunoprecipitation, and immunofluorescence assays. Its polyclonal nature ensures a broad spectrum of binding capabilities, making it an excellent choice for diverse experimental needs.

Whether you're investigating transmembrane transport mechanisms, studying cellular detoxification processes, or exploring disease pathways, our Anti-ABCC6 Antibody is your reliable research partner. Its high-quality formulation and generous 100µg size make it an indispensable tool in your laboratory, enabling you to make significant contributions to the field of cell biology.

Empower your research with the precision and reliability of our Anti-ABCC6 Antibody. Order your 100µg supply today and embark on a journey of discovery with the confidence that you have a trusted ally in your scientific pursuits.

Product Name

ABCC6 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

The ATP-binding cassette transporter 6 (ABCC6) gene, also named as MRP6, is a cellular transmembrane protein transporter and belongs to ATP-binding cassette (ABC) family. ABCC6 is an ATP-dependent transporter contains two ATP-binding domains. It is mainly found in the liver, the proximal tubules of the kidneys and the intestines. ABCC6 is involved in a pathway of extracellular nucleotide metabolism and the regulation of tissue calcification. Mutations of ABCC6 leads to pseudoxanthoma elasticum (PXE) which is a rare autosomal recessive disorder. Mutations of ABCC6 can also lead generalized arterial calcification of infancy-2 (GACI2).

IMMUNOGEN INFORMATION

Immunogen

ATP-binding cassette, sub-family C (CFTR/MRP), member 6

Synonyms

ABC34, ABCC6, ARA, EST349056, MLP1, MOAT E, MOATE, MRP6, PXE, PXE1

Observed MW

165 kDa

APPLICATION

Tested Application

ELISA, IHC

Recommended Dilution

IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

O95255

IMAGES