anti- ALPL antibody

Embark on a journey into the world of alkaline phosphatases with our highly specialized Anti-ALPL Antibody, now available in a convenient 100µg size. ALPL, also known as tissue-nonspecific alkaline phosphatase, is a ubiquitous enzyme involved in various physiological and pathological processes, including bone mineralization and liver function. This meticulously crafted antibody offers exceptional specificity and sensitivity, making it an ideal choice for a wide range of research applications, from immunohistochemistry to enzyme activity assays.

What sets our Anti-ALPL Antibody apart is its outstanding performance. It has undergone rigorous validation and testing to ensure consistent and reproducible results, effectively reducing experimental variability and optimizing resource utilization.

With a generous 100µg size, this product provides an ideal balance between cost-effectiveness and practicality, offering ample antibody for multiple experiments while minimizing wastage, aligning with our commitment to sustainable research practices.

Engineered for user-friendliness, our Anti-ALPL Antibody is suitable for researchers of all experience levels, from newcomers to seasoned scientists. It seamlessly integrates into various laboratory techniques, enhancing the precision and reliability of your experiments.

Contribute to a deeper understanding of enzyme biology and its pivotal roles in health and disease with confidence, knowing you have the support of a high-quality, meticulously crafted Anti-ALPL Antibody. Drive advances in enzymology research and be part of groundbreaking discoveries in tissue-specific enzyme regulation.

Product Name

ALPL antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney(tissue non-specific). The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. ALPL(Alkaline phosphatase, tissue-nonspecific isozyme) is also named as AP-TNAP, TNSALP and belongs to the alkaline phosphatase family. It can exsit as a homodimer with the molecular weight of 140 kDa(PMID:18724009). ALPL was synthesized as a 66-kDa endo-b-N-acetylglucos-aminidase H(Endo H)-sensitive form, and processed to an 80-kDa mature form, which is anchored to the plasma membrane via glycosylphosphatidylinositol(GPI)(PMID:10839996).This antibody can bind the four mentioned alkaline phosphatases.

IMMUNOGEN INFORMATION

Immunogen

alkaline phosphatase, liver/bone/kidney

Synonyms

Alkaline phosphatase, Alkaline phosphatase liver/bone/kidney isozyme, Alkaline phosphatase tissue nonspecific isozyme, ALPL, BLAP, Bone Alkaline Phosphatase, NBAP

Observed MW

45-60 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500-1:2000; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

P05186

IMAGES