anti- BACE1 antibody

Investigate BACE1 with precision using our Monoclonal Anti-BACE1 Antibody. This 100µg antibody is your tool for unraveling the roles of BACE1, a critical enzyme involved in the proteolytic processing of amyloid precursor protein (APP), a process associated with Alzheimer's disease.

Engineered for accuracy and reliability, this monoclonal antibody excels in a range of applications, from Western blotting to immunohistochemistry. Its high specificity and sensitivity ensure that your experiments yield accurate and reproducible results, making it an indispensable addition to your research.

BACE1 is a key player in Alzheimer's disease research, where its inhibition is a promising therapeutic strategy. With this monoclonal antibody in your toolkit, you're better equipped to explore BACE1 functions. Whether you're investigating amyloid-beta production or studying drug development, this antibody is your trusted research companion.

Elevate your scientific endeavors by ordering your Monoclonal Anti-BACE1 Antibody today and gain deeper insights into the complex world of BACE1 biology.

Product Name

BACE1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Responsible for the proteolytic processing of the amyloid precursor protein(APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.

IMMUNOGEN INFORMATION

Immunogen

beta-site APP-cleaving enzyme 1

Synonyms

BACE, KIAA1149

Observed MW

50-55 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

UNIPROT INFORMATION

UniProt ID

P56817

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