Anti-CD137 antibody

Product Name

CD137 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB.

IMMUNOGEN INFORMATION

Immunogen

Tumor necrosis factor receptor superfamily member 9

Synonyms

TNFRSF9, 4-1BB, CD137, CDw137, ILA

Observed MW

27 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500-1:2000; IHC: 1:50-1:200

UNIPROT INFORMATION

UniProt ID

Q07011

IMAGES

Immunohistochemistry of paraffin-embedded mouse spleen tissue slide using FNab10476( CD137 Antibody) at dilution of 1:200

mouse spleen tissue were subjected to SDS PAGE followed by western blot with FNab10476(CD137 antibody) at dilution of 1:1000