anti-Phospho-Camk2a-T286 antibody

Product Name

Phospho-Camk2a(T286) antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene.

IMMUNOGEN INFORMATION

Immunogen

calcium/calmodulin-dependent protein kinase II alpha

Synonyms

CaM kinase II subunit alpha, CaMK II subunit alpha, CAMK2, CAMK2A, CAMK2B, CAMK2D, CAMK2G, CAMKA, CaMKII alpha, KIAA0968

Observed MW

54 kDa

APPLICATION

Tested Application

ELISA, WB

Recommended Dilution

WB: 1:500-1:2000

UNIPROT INFORMATION

UniProt ID

Q9UQM7

IMAGES

mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab10481(Phospho-Camk2a-T286 antibody) at dilution of 1:1000