anti-IL-13 antibody

Product Name

IL-13 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4.

IMMUNOGEN INFORMATION

Immunogen

Interleukin-13

Synonyms

IL13, IL-13, P600

Observed MW

16 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500-1:2000; IHC: 1:50-1:200

UNIPROT INFORMATION

UniProt ID

P35225

IMAGES

Immunohistochemistry of paraffin-embedded rat brain tissue slide using FNab10489(IL-13 antibody) at dilution of 1:50

Mouse pancreas tissue were subjected to SDS PAGE followed by western blot with FNab10489(IL-13 antibody) at dilution of 1:1000