anti-KNG1 antibody

Product Name

KNG1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

This gene uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. Bradykinin also functions as an antimicrobial peptide with antibacterial and antifungal activity. In contrast to HMWK, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene.

IMMUNOGEN INFORMATION

Immunogen

Kininogen-1

Synonyms

KNG1, BDK, BK, KNG

Observed MW

68 kDa

APPLICATION

Tested Application

ELISA, WB, IF

Recommended Dilution

WB: 1:500-1:2000; IF: 1:50-1:200

UNIPROT INFORMATION

UniProt ID

P01042

IMAGES

Immunofluorescent analysis of L929 cells using FNab10493(KNG1 antibody) at dilution of 1:50.

HT-29 cells were subjected to SDS PAGE followed by western blot with FNab10493(KNG1 antibody) at dilution of 1:1000