anti-MMP16 antibody

Product Name

MMP16 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The encoded protein activates MMP2 by cleavage. This gene was once referred to as MT-MMP2, but was renamed as MT-MMP3 or MMP16.

IMMUNOGEN INFORMATION

Immunogen

Matrix metalloproteinase-16

Synonyms

MMP16, C8orf57, MMP-X2, MT-MMP2, MT-MMP3, MT3-MMP

Observed MW

60 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF

Recommended Dilution

WB: 1:500-1:2000; IHC: 1:50-1:200; IF: 1:50-1:200

UNIPROT INFORMATION

UniProt ID

P51512

IMAGES

Immunohistochemistry of paraffin-embedded human breast cancer slide using FNab10494( MMP16 Antibody) at dilution of 1:200

HT-1080 cells were subjected to SDS PAGE followed by western blot with FNab10494( MMP16 Antibody) at dilution of 1:1000