anti- GSK3B antibody

Product Name

GSK3B antibody

Size

100µg

Form

liquid

Purification

Protein A+G purification

Purity

≥95% as determined by SDS-PAGE

Host

Mouse

Clonality

monoclonal

Isotype

IgG1

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

IMMUNOGEN INFORMATION

Immunogen

glycogen synthase kinase 3 beta

Observed MW

47 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF

Recommended Dilution

WB: 1:500-1:2000; IHC: 1:50-1:200; IF: 1:50-1:200

UNIPROT INFORMATION

UniProt ID

P49841

IMAGES

Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using FNab10503( GSK3B Antibody) at dilution of 1:100

Immunofluorescent analysis of Hela cells using FNab10503(GSK3B antibody) at dilution of 1:50.

Hela cells were subjected to SDS PAGE followed by western blot with FNab10503(GSK3B antibody) at dilution of 1:1000