anti-L-Selectin antibody

Product Name

L-Selectin antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

This gene encodes a cell surface adhesion molecule that belongs to a family of adhesion/homing receptors. The encoded protein contains a C-type lectin-like domain, a calcium-binding epidermal growth factor-like domain, and two short complement-like repeats. The gene product is required for binding and subsequent rolling of leucocytes on endothelial cells, facilitating their migration into secondary lymphoid organs and inflammation sites. Single-nucleotide polymorphisms in this gene have been associated with various diseases including immunoglobulin A nephropathy. Alternatively spliced transcript variants have been found for this gene.

IMMUNOGEN INFORMATION

Immunogen

L-selectin

Synonyms

SELL, CD62L, LAM1, LECAM1, LEU8, LNHR

Observed MW

74 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF

Recommended Dilution

WB: 1:500-1:2000; IHC: 1:50-1:200; IF: 1:50-1:200

UNIPROT INFORMATION

UniProt ID

P14151

IMAGES

Immunohistochemistry of paraffin-embedded human gastric cancer slide using FNab10510(L-Selectin antibody) at dilution of 1:50

Immunofluorescent analysis of NIH/3T3 cells using FNab10510(L-Selectin antibody) at dilution of 1:50.

Raji cells were subjected to SDS PAGE followed by western blot with FNab10510(L-Selectin antibody) at dilution of 1:1000