anti- CSPG4 antibody

Enter the fascinating realm of proteoglycans and cell surface receptors with our Anti-CSPG4 Antibody, now available in a convenient 100µg size. CSPG4 (Chondroitin Sulfate Proteoglycan 4), a multifunctional cell surface proteoglycan, is involved in diverse cellular processes, including cell adhesion, migration, and signal transduction.

This meticulously designed antibody is rigorously validated for specificity and sensitivity, making it suitable for various applications, including immunofluorescence, studies of cellular interactions, and investigations into cancer progression and stem cell biology. Whether you are researching melanoma, stem cell niches, or the functions of CSPG4 in cell behavior, our Anti-CSPG4 Antibody will provide you with precise and reproducible results.

Rely on the accuracy and reliability of this antibody as you advance your research in cancer biology, regenerative medicine, and related fields. Uncover the multifaceted roles of CSPG4 in health and disease, and explore its potential as a therapeutic target or diagnostic marker with the assistance of this high-quality antibody.

Product Name

CSPG4 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

CSPG4, also named as HMW-MAA, MCSP, MCSPG, MEL-CSPG, MSK16 and NG2, is a proteoglycan playing a role in cell proliferation and migration which stimulates endothelial cells motility during microvascular morphogenesis. CSPG4 may inhibit neurite outgrowth and growth cone collapse during axon regeneration. It is cell surface receptor for collagen alpha 2(VI) which may confer cells ability to migrate on that substrate. CSPG4 may regulate MPP16-dependent degradation and invasion of type I collagen participating in melanoma cells invasion properties. It modulates the plasminogen system by enhancing plasminogen activation and inhibiting angiostatin.

IMMUNOGEN INFORMATION

Immunogen

chondroitin sulfate proteoglycan 4

Synonyms

CSPG4, HMW MAA, MCSP, MCSPG, MEL CSPG, MSK16, NG2

Observed MW

270kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF

Recommended Dilution

WB: 1:500-1:2000; IHC: 1:50-1:200; IF: 1:50-1:500

UNIPROT INFORMATION

UniProt ID

Q6UVK1

IMAGES

Immunohistochemistry of paraffin-embedded human kidney slide using FNab10522(CSPG4 antibody) at dilution of 1:100

Immunofluorescent analysis of Hela cells using FNab10522(CSPG4 antibody) at dilution of 1:50.

Hela cells were subjected to SDS PAGE followed by western blot with FNab10522(CSPG4 antibody) at dilution of 1:1000