anti- Connexin-43 antibody

Enter the world of intercellular communication and cardiac function with our Anti-Connexin-43 Antibody, meticulously developed and conveniently available in a 100µg size. Connexin-43, a major constituent of gap junctions in the heart, plays a pivotal role in synchronizing electrical impulses between cardiomyocytes and ensuring proper cardiac function. This high-quality antibody serves as your essential tool for investigating the intricate processes of cardiac conduction and its implications in heart health.

Our antibody is meticulously crafted and rigorously validated to ensure specificity and sensitivity, guaranteeing accurate and reproducible results in your research. Whether you're exploring cardiac arrhythmias, heart development, or the role of Connexin-43 in cardiac diseases, this antibody is your dependable research companion.

The 100µg size provides a substantial supply of antibody for your experiments, reducing the inconvenience of frequent reordering and ensuring uninterrupted progress in your research endeavors. Choose our Anti-Connexin-43 Antibody to advance your scientific exploration of intercellular communication in the heart and contribute to a deeper understanding of cardiac physiology.

Unraveling the intricacies of Connexin-43's role in cardiac conduction and its impact on heart health is essential for deciphering the complexities of cardiovascular diseases and their implications for patient care. Our antibody empowers you to delve into this intriguing area of research, potentially paving the way for novel therapeutic strategies and improved cardiac treatments.

Product Name

Connexin-43 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Gap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph. Negative regulator of bladder functional capacity: acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural stimuli and causing them to contract(By similarity). May play a role in cell growth inhibition through the regulation of NOV expression and localization. Plays an essential role in gap junction communication in the ventricles(By similarity).

IMMUNOGEN INFORMATION

Immunogen

gap junction protein, alpha 1, 43kDa

Synonyms

Connexin-43, CX43, DFNB38, Gap junction alpha 1 protein, GJA1, GJAL, ODDD

Observed MW

47 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF

Recommended Dilution

WB: 1:500-1:2000; IF: 1:50-1:500

UNIPROT INFORMATION

UniProt ID

P17302

IMAGES

Immunofluorescent analysis of Hela cells using FNab10703(Connexin-43 antibody) at dilution of 1:50.

Rat brain tissue were subjected to SDS PAGE followed by western blot with FNab10703(Connexin-43 antibody) at dilution of 1:1000