anti- CYP24A1 antibody

Our Anti-CYP24A1 Antibody, available in a 100µg size, is a valuable tool for researchers exploring the cytochrome P450 enzyme CYP24A1, known for its central role in vitamin D metabolism and regulation.

CYP24A1 is responsible for the breakdown of the active form of vitamin D, calcitriol, thereby controlling calcium and phosphate homeostasis, bone health, and immune system modulation. Understanding the functions and regulation of CYP24A1 is essential for unraveling its contributions to vitamin D metabolism and its implications in skeletal and immune disorders.

Our antibody has been meticulously validated for specificity and sensitivity, ensuring reliable results in your experiments. Its compact size allows for versatility in applications, whether you're conducting vitamin D metabolism studies, investigating bone health, or exploring the immune-modulating effects of vitamin D. Trust in the quality of our Anti-CYP24A1 Antibody to accelerate your scientific investigations and contribute to advancements in vitamin D research and immunology.

Product Name

CYP24A1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein initiates the degradation of 1, 25-dihydroxyvitamin D3, the physiologically active form of vitamin D3, by hydroxylation of the side chain. In regulating the level of vitamin D3, this enzyme plays a role in calcium homeostasis and the vitamin D endocrine system. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

IMMUNOGEN INFORMATION

Immunogen

cytochrome P450, family 24, subfamily A, polypeptide 1

Synonyms

24 OHase, CP24, CYP24, CYP24A1, Cytochrome P450 24A1, Cytochrome P450 CC24, P450 CC24, Vitamin D(3) 24 hydroxylase

Observed MW

43 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

UNIPROT INFORMATION

UniProt ID

Q07973

IMAGES

Immunohistochemistry of paraffin-embedded human kidney tissue slide using FNab10704(CYP24A1 antibody) at dilution of 1:100

Mouse liver tissue were subjected to SDS PAGE followed by western blot with FNab10704(CYP24A1 antibody) at dilution of 1:1000