anti- Galc antibody

Delve into the world of Galc (Galactocerebrosidase) and its pivotal role in myelin metabolism with our Anti-Galc Antibody, available in a 100µg size. Galc is a lysosomal enzyme essential for the breakdown of galactolipids in the nervous system, and its deficiency is associated with demyelinating diseases. This antibody is meticulously designed to specifically target Galc, allowing you to study its functions with precision.

Key Features:

• Precise Targeting: Rigorously validated to exclusively recognize Galc, reducing the risk of non-specific binding to other proteins.
• Versatile Applications: Suitable for various experimental techniques, including immunohistochemistry, enzyme assays, and immunoprecipitation, empowering your research in neurobiology and neurodegenerative diseases.
• Adequate Quantity: With 100µg of antibody, you have ample material for multiple experiments, reducing the need for frequent restocking.
• Quality Assurance: Manufactured under stringent quality control measures to ensure the consistency and reliability of your results.
• Uncover Myelin Function: Whether you're investigating Galc's role in Krabbe disease, leukodystrophies, or central nervous system disorders, our Anti-Galc Antibody is your trusted partner.
  
  

  Product Name

  Galc antibody

  Size

  100µg

  Form

  liquid

  Purification

  Immunogen affinity purified

  Purity

  ≥95% as determined by SDS-PAGE

  Host

  Rabbit

  Clonality

  polyclonal

  Isotype

  IgG

  Storage

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

  BACKGROUND

  This gene encodes a lysosomal protein which hydrolyzes the galactose ester bonds of galactosylceramide, galactosylsphingosine, lactosylceramide, and monogalactosyldiglyceride. Mutations in this gene have been associated with Krabbe disease, also known as globoid cell leukodystrophy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

  IMMUNOGEN INFORMATION

  Immunogen

  galactosylceramidase

  Synonyms

  Gacy, galactosylceramidase, Galc, twi, twitcher

  Observed MW

  80 kDa, 50 kDa, 30 kDa

  APPLICATION

  Tested Application

  ELISA, WB, IHC

  Recommended Dilution

  WB: 1:500 - 1:2000; IHC: 1:50 - 1:100

  UNIPROT INFORMATION

  UniProt ID

  P54803

  IMAGES
  
  

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  Immunohistochemistry of paraffin-embedded human liver tissue slide using FNab10708(Galc antibody) at dilution of 1:100
  
  

  Rat testis tissue were subjected to SDS PAGE followed by western blot with FNab10708(Galc antibody) at dilution of 1:1000