anti- CD79A antibody

Venture into the intricacies of B-cell immunology and B-cell receptor signaling with our Anti-CD79A Antibody, available in a 100µg size. CD79A, also known as Ig-alpha, is a crucial component of the B-cell receptor complex, and this highly specific monoclonal antibody offers precise targeting for your research needs.

Whether you're conducting flow cytometry, immunohistochemistry, or Western blotting, this antibody delivers consistent and dependable results. It is an indispensable tool for advancing your understanding of CD79A-mediated B-cell functions and immune responses.

Empower your research and contribute to scientific advancements with the trusted performance of our Anti-CD79A Antibody. With this tool at your disposal, you'll be better equipped to unravel the complexities of CD79A-mediated B-cell receptor signaling and its implications in autoimmune diseases and B-cell malignancies.

Product Name

CD79A antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex(BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro-and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts with and increases activity of some Src-family tyrosine kinases. Represses BCR signaling during development of immature B-cells.

IMMUNOGEN INFORMATION

Immunogen

CD79a molecule, immunoglobulin-associated alpha

Synonyms

CD79A, Ig alpha, IGA, MB 1, MB 1 membrane glycoprotein, MB1, Surface IgM associated protein

Observed MW

40 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500-1:2000; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

P11912

IMAGES

Immunohistochemistry of paraffin-embedded rat spleen tissue slide using FNab10737(CD79A antibody) at dilution of 1:100

Mouse spleen were subjected to SDS PAGE followed by western blot with FNab10737(CD79A antibody) at dilution of 1:1000