anti- DNMT3A antibody

Unlock the secrets of epigenetic control and gene regulation with our meticulously crafted Anti-DNMT3A Antibody, now available in a 100µg size. DNA (cytosine-5-)-methyltransferase 3A (DNMT3A) is a critical enzyme that catalyzes DNA methylation, influencing epigenetic patterns during development and cellular differentiation.

This antibody offers exceptional specificity and sensitivity, ensuring precise detection of DNMT3A in your experiments. Whether you're investigating epigenetic regulation, hematopoiesis, or cancer epigenomics, this antibody is your key to unlocking the mysteries of these essential biological processes.

Our high-quality Anti-DNMT3A Antibody undergoes stringent quality control to guarantee consistent and reproducible results, enabling you to advance your research with confidence. Delve into the dynamic world of DNA methylation and the central role DNMT3A plays in shaping the epigenome. Whether you're studying epigenetic reprogramming, chromatin modifications, or epigenetic therapy, this antibody is an indispensable tool for your research.

Product Name

DNMT3A antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated.

IMMUNOGEN INFORMATION

Immunogen

DNA (cytosine-5-)-methyltransferase 3 alpha

Synonyms

DNMT3A2

APPLICATION

Tested Application

ELISA, IHC

Recommended Dilution

IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q9Y6K1

IMAGES

Immunohistochemistry of paraffin-embedded mouse heart using FNab10773(DNMT3A antibody) at dilution of 1:100