anti- CFHR3 antibody

Embark on a journey into the world of complement factor H-related proteins with our Anti-CFHR3 Antibody. CFHR3 is a member of the complement factor H family, and its dysregulation has been implicated in various complement-related disorders. This 100µg antibody is your essential tool for investigating CFHR3's roles in immune function and disease.

Our Anti-CFHR3 Antibody has undergone rigorous validation to ensure specificity and sensitivity, making it suitable for various applications, including Western blotting and immunofluorescence. With 100µg of this high-quality antibody, you'll have an ample supply for multiple experiments, ensuring consistent and robust results.

CFHR3's involvement in complement regulation and immune function makes it a critical player in understanding the mechanisms underlying complement-related disorders. Investigating CFHR3 can provide valuable insights into disease pathogenesis and potential therapeutic avenues.

Trust in our antibodies to advance your research. With precision and reliability, our Anti-CFHR3 Antibody will empower you to explore the intricate world of complement factor H-related proteins.

Product Name

CFHR3 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

The protein encoded by this gene is a secreted protein, which belongs to the complement factor H-related protein family. It binds to heparin, and may be involved in complement regulation. Mutations in this gene are associated with decreased risk of age-related macular degeneration, and with an increased risk of atypical hemolytic-uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

IMMUNOGEN INFORMATION

Immunogen

CFHR3

Synonyms

CFHL3, DOWN16, FHR-3, FHR3, HLF4

Observed MW

45 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF

Recommended Dilution

WB: 1:500-1:2000; IHC: 1:50-1:500; IF: 1:50-1:100

UNIPROT INFORMATION

UniProt ID

Q02985

IMAGES

Immunohistochemistry of paraffin-embedded human kidney tissue slide using FNab10775(CFHR3 Antibody) at dilution of 1:100.

Various lysates were subjected to SDS PAGE followed by western blot with FNab10775(CFHR3 antibody) at dilution of 1:1000