anti- PGC1a antibody

Product Name

PGC1a antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

PPARGC1A, also named as Peroxisome proliferator-activated receptor gamma coactivator 1-alpha, is a 798 amino acid protein, which Contains 1 RRM(RNA recognition motif) domain and localizes in the nucleus. PPARGC1A is transcriptional coactivator for steroid receptors and nuclear receptors. PPARGC1A can regulate key mitochondrial genes that contribute to the program of adaptive thermogenesis and plays an essential role in metabolic reprogramming in response to dietary availability through coordination of the expression of a wide array of genes involved in glucose and fatty acid metabolism.

IMMUNOGEN INFORMATION

Immunogen

peroxisome proliferator-activated receptor gamma, coactivator 1 alpha

Synonyms

LEM6, Ligand effect modulator 6, PGC 1 alpha, PGC 1(alpha), PGC 1v, PGC1, PGC1A, PPAR gamma coactivator 1 alpha, PPARGC 1 alpha, PPARGC1, PPARGC1A

Observed MW

45kDa,110-120 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1：200-1：2000; IHC: 1：20-1：200

UNIPROT INFORMATION

UniProt ID

Q9UBK2

IMAGES

Immunohistochemistry of paraffin-embedded human kidney using FNab10788(PGC1A antibody) at dilution of 1:100

HeLa cells were subjected to SDS PAGE followed by western blot with FNab10788(PGC1a Antibody) at dilution of 1:1000