anti- ERAB antibody

Embark on a journey into the world of fatty acid metabolism and cellular energy production with our Anti-ERAB Antibody, an essential tool for studying ERAB, a key enzyme in the beta-oxidation pathway. With 100µg of high-quality antibody, you have the precision and reliability required for your experiments.

ERAB is critical for the breakdown of fatty acids, contributing to energy production and lipid metabolism. Our antibody is meticulously tested for specificity and sensitivity, making it ideal for techniques such as immunoblotting, immunoprecipitation, and immunofluorescence.

The Anti-ERAB Antibody is your gateway to unraveling the functions of ERAB and its role in cellular energy production. Whether you're involved in basic research or metabolic disease studies, this antibody is an invaluable asset, providing you with the confidence to advance your scientific inquiries and make significant strides in your work.

Product Name

ERAB antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Functions in mitochondrial tRNA maturation. Part of mitochondrial ribonuclease P, an enzyme composed of MRPP1/TRMT10C, MRPP2/HSD17B10 and MRPP3/KIAA0391, which cleaves tRNA molecules in their 5'-ends. Catalyzes the beta-oxidation at position 17 of androgens and estrogens and has 3-alpha-hydroxysteroid dehydrogenase activity with androsterone. Catalyzes the third step in the beta-oxidation of fatty acids. Carries out oxidative conversions of 7-alpha-OH and 7-beta-OH bile acids. Also exhibits 20-beta-OH and 21-OH dehydrogenase activities with C21 steroids. By interacting with intracellular amyloid-beta, it may contribute to the neuronal dysfunction associated with Alzheimer disease(AD).

IMMUNOGEN INFORMATION

Immunogen

hydroxysteroid(17-beta) dehydrogenase 10

Synonyms

17 beta HSD 10, 17b HSD10, ABAD, CAMR, DUPXp11.22, ERAB, HADH2, HCD2, HSD17B10, MHBD, MRPP2, MRX17, MRX31, MRXS10, SCHAD, SDR5C1, Type II HADH, XH98G2

Observed MW

27 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

Q99714

IMAGES

Immunohistochemistry of paraffin-embedded rat lung using FNab10790(ERAB antibody) at dilution of 1:100

293T cells were subjected to SDS PAGE followed by western blot with FNab10790(ERAB antibody) at dilution of 1:1000