anti- CD8 antibody

Uncover the mysteries of T-cell immunology and cytotoxic T lymphocytes with our Anti-CD8 Antibody, now available in a 100µg size. CD8 is a critical surface marker on cytotoxic T cells, and this highly specific monoclonal antibody offers precise targeting for your research needs.

Whether you're involved in flow cytometry, immunohistochemistry, or functional assays, this antibody provides consistent and dependable results. It is an indispensable tool for advancing your understanding of CD8-mediated immune responses and its implications in infection and cancer immunotherapy.

Trust in the quality and performance of our Anti-CD8 Antibody to advance your research in immunology and cytotoxicity. With this essential reagent at your disposal, you can unravel the complexities of CD8-mediated immune regulation and immune cell function.

Product Name

CD8 antibody

Size

100µg

Form

liquid

Purification

protein A+G purified

Purity

≥95% as determined by SDS-PAGE

Host

mouse

Clonality

monoclonal

Isotype

IgG1

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

BACKGROUND

The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene.

IMMUNOGEN INFORMATION

Immunogen

CD8a molecule

Synonyms

CD8, Leu2, MAL, p32

Observed MW

30 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500 - 1:2000; IHC: 1:500 - 1:2000

UNIPROT INFORMATION

UniProt ID

P01732

IMAGES

Immunohistochemistry of paraffin-embedded human breast cancer using FNab10807(CD8 antibody) at dilution of 1:1000

MOLT-4 cell lysates were subjected to SDS PAGE followed by western blot with FNab10807(CD8 antibody) at dilution of 1:1000