anti- ARG1 antibody

Delve into the intricacies of arginine metabolism and immune regulation with our Anti-ARG1 Polyclonal Antibody, available in a convenient 100µg size. Arginase 1 (ARG1) is a critical enzyme involved in the conversion of arginine to ornithine and urea, influencing immune responses and tissue repair.

This polyclonal antibody, raised in rabbits, offers exceptional sensitivity and specificity, ensuring accurate and reproducible results in various applications, from Western blotting to immunohistochemistry. Whether you're investigating ARG1's role in wound healing or its implications in immunosuppression, our antibody is your dependable research partner.

The 100µg size provides cost-effective versatility, catering to both small-scale experiments and larger research projects. Its consistent quality and purity make it a reliable choice for researchers across diverse disciplines, from immunology to regenerative medicine.

Choose our Anti-ARG1 Polyclonal Antibody to advance your research and gain deeper insights into ARG1-related processes. Count on its performance and join the ranks of scientists who rely on our products to advance scientific understanding.

Product Name

ARG1 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Arginase-1(Liver arginase) belongs to the arginase family. ARG1 is a novel immunohistochemical marker of hepatocellular differentiation in fine needle aspiration cytology and a marker of hepatocytes and hepatocellular neoplasms. ARG1 is closely associated with alternative macrophage activation(PMID:12098359) and ARG1 has been shown to protectmotor neurons from trophic factor deprivation and allow sensory neurons to overcome neurite outgrowth inhibition by myelin proteins(PMID: 20071539).It can exsit as a homotrimer(PMID:16141327) and it has 3 isoforms produced by alternative splicing.Defects in ARG1 are the cause of argininemia(ARGIN). Deletion or TNF-mediated restriction of ARG1 unleashes the production of NO by NOS2, which is critical for pathogen control.(PMID:27117406).

IMMUNOGEN INFORMATION

Immunogen

arginase, liver

Synonyms

ARG1, Arginase 1, liver Arginase, Liver type arginase

Observed MW

25-40 kDa

APPLICATION

Tested Application

ELISA, IF, WB

Recommended Dilution

WB: 1:500-1:2000; IF: 1:20-1:200

UNIPROT INFORMATION

UniProt ID

P05089

IMAGES

HepG2 cells were subjected to SDS PAGE followed by western blot with FNab10829(ARG1 antibody) at dilution of 1:1000