anti- HGF antibody

Product Name

HGF antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

BACKGROUND

This gene encodes a protein that binds to the hepatocyte growth factor receptor to regulate cell growth, cell motility and morphogenesis in numerous cell and tissue types. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate alpha and beta chains, which form the mature heterodimer. This protein is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. This protein also plays a role in angiogenesis, tumorogenesis, and tissue regeneration. Although the encoded protein is a member of the peptidase S1 family of serine proteases, it lacks peptidase activity. Mutations in this gene are associated with nonsyndromic hearing loss.

IMMUNOGEN INFORMATION

Immunogen

Hepatocyte growth factor

Synonyms

HGF, DFNB39, F-TCF, HGFB, HPTA, SF

Observed MW

54 kDa

APPLICATION

Tested Application

ELISA, WB, IHC, IF

Recommended Dilution

WB: 1:500-1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200

UNIPROT INFORMATION

UniProt ID

P14210

IMAGES

Immunohistochemistry of paraffin-embedded rat kidney tissue using FNab10911(HGF Antibody) at dilution of 1:100

Various lysates were subjected to SDS PAGE followed by western blot with FNab10911(HGF Antibody) at dilution of 1:1000