anti- ERCC2 antibody

Delve into the world of DNA repair and genomic stability with our Anti-ERCC2 Antibody, a critical tool for studying ERCC2, a key component of the DNA repair machinery. With 100µg of high-quality antibody, you have the precision and reliability required for your experiments.

ERCC2 plays a pivotal role in repairing DNA damage, preventing mutations, and maintaining genomic integrity. Our antibody is meticulously tested for specificity and sensitivity, making it ideal for techniques such as immunoblotting, immunoprecipitation, and immunofluorescence.

The Anti-ERCC2 Antibody is your gateway to unraveling the functions of ERCC2, contributing to a deeper understanding of DNA repair and genome stability. Whether you're engaged in basic research or oncology studies, this antibody is a valuable asset, providing you with the confidence to advance your scientific inquiries and make significant strides in your work.

Product Name

ERCC2 antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

ATP-dependent 5'-3' DNA helicase, component of the core-TFIIH basal transcription factor. Involved in nucleotide excision repair(NER) of DNA by opening DNA around the damage, and in RNA transcription by RNA polymerase II by anchoring the CDK-activating kinase(CAK) complex, composed of CDK7, cyclin H and MAT1, to the core-TFIIH complex. Involved in the regulation of vitamin-D receptor activity. As part of the mitotic spindle-associated MMXD complex it plays a role in chromosome segregation. Might have a role in aging process and could play a causative role in the generation of skin cancers.

IMMUNOGEN INFORMATION

Immunogen

excision repair cross-complementing rodent repair deficiency, complementation group 2

Synonyms

XPD, XPDC

Observed MW

80 kDa

APPLICATION

Tested Application

ELISA, WB

Recommended Dilution

WB: 1:500-1:2000

UNIPROT INFORMATION

UniProt ID

P18074

IMAGES