anti- CHRNE antibody

Uncover the intricacies of neuromuscular junctions with our Anti-CHRNE Antibody, available in a 100µg size. The cholinergic receptor nicotinic epsilon subunit (CHRNE) is a pivotal component of the neuromuscular junction, essential for muscle contraction and motor control.

This high-quality antibody is meticulously designed to provide exceptional specificity and sensitivity, ensuring accurate detection of CHRNE protein in your experiments. Researchers investigating neuromuscular physiology, motor function, or related fields will appreciate the precision and reliability of this antibody.

Our Anti-CHRNE Antibody undergoes rigorous quality control, guaranteeing consistent and reproducible results. Take your research on neuromuscular transmission and muscle function to the next level with this essential tool.

Product Name

CHRNE antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Acetylcholine receptors at mature mammalian neuromuscular junctions are pentameric protein complexes composed of four subunits in the ratio of two alpha subunits to one beta, one epsilon, and one delta subunit. The acetylcholine receptor changes subunit composition shortly after birth when the epsilon subunit replaces the gamma subunit seen in embryonic receptors. Mutations in the epsilon subunit are associated with congenital myasthenic syndrome.

IMMUNOGEN INFORMATION

Immunogen

Acetylcholine receptor subunit epsilon

Synonyms

CHRNE, ACHRE, CMS1D, CMS1E, CMS2A, CMS4A, CMS4B, CMS4C, FCCMS, SCCMS

Observed MW

45 kDa

APPLICATION

Tested Application

WB

Recommended Dilution

WB: 1:500-1:2000

UNIPROT INFORMATION

UniProt ID

Q04844

IMAGES

Various lysates were subjected to SDS PAGE followed by western blot with FNab10937( CHRNE Antibody) at dilution of 1:1000.