anti- Mesothelin antibody

Product Name

Mesothelin antibody

Size

100µg

Form

liquid

Purification

Immunogen affinity purified

Purity

≥95% as determined by SDS-PAGE

Host

Rabbit

Clonality

polyclonal

Isotype

IgG

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

BACKGROUND

Mesothelin (MSLN) is a 40kDa GPI-anchored surface glycoprotein that is expressed on pleural and peritoneal mesothelial cells, but not in other non-neoplastic tissues. The mesothelin gene encodes a 69-71kDa precursor protein that is processed to a 40kDa membrane-bound protein termed mesothelin and a 31kDa shed fragment called megakaryocyte-potentiating factor (MPF) that is released from the cell.

IMMUNOGEN INFORMATION

Immunogen

Mesothelin

Synonyms

CAK1, CAK1 antigen, mesothelin, MPF, MPF Mesothelin, cleaved form, MSLN, SMR

Observed MW

70 kDa, 40 kDa

APPLICATION

Tested Application

ELISA, WB, IHC

Recommended Dilution

WB: 1:500-1:2000; IHC: 1:50 - 1:200

UNIPROT INFORMATION

UniProt ID

Q13421

IMAGES

Immunohistochemistry of paraffin-embedded human ovary tumor using FNab10954 at dilution of 1:100

OVCAR3 cells tissue were subjected to SDS PAGE followed by western blot with FNab10954 at dilution of 1:1000