VE-Cadherin mouse Monoclonal Antibody(8E5)

This gene encodes a classical cadherin of the cadherin superfamily. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion molecule is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classical cadherin by imparting to cells the ability to adhere in a homophilic manner, this protein plays a role in endothelial adherens junction assembly and maintenance. This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer.

The VE-Cadherin Mouse Monoclonal Antibody (8E5) is a highly specific and reliable tool for the detection and analysis of VE-Cadherin protein expression. This antibody is produced using advanced monoclonal antibody technology, ensuring exceptional quality and consistency.

VE-Cadherin, also known as Cadherin-5 or CDH5, is a transmembrane glycoprotein that plays a crucial role in endothelial cell adhesion and vascular development. It is primarily expressed in endothelial cells and is essential for the formation and maintenance of adherens junctions.

The VE-Cadherin Mouse Monoclonal Antibody (8E5) has been extensively validated for various applications, including immunohistochemistry, immunofluorescence, and western blotting. It exhibits high specificity and sensitivity, enabling accurate and reliable detection of VE-Cadherin protein in various sample types.

This antibody offers numerous advantages, including its monoclonal nature, which ensures batch-to-batch consistency and eliminates the risk of non-specific binding. It also demonstrates excellent affinity and selectivity towards VE-Cadherin, enabling precise and specific detection without cross-reactivity with other proteins.

The VE-Cadherin Mouse Monoclonal Antibody (8E5) is supplied as a ready-to-use solution, allowing for convenient and efficient usage. It is provided in a liquid format, eliminating the need for reconstitution and minimizing the risk of sample contamination.

With its exceptional performance and reliability, the VE-Cadherin Mouse Monoclonal Antibody (8E5) is an indispensable tool for researchers and scientists studying endothelial cell biology, vascular development, and related fields. Its high specificity and sensitivity make it an ideal choice for accurate and reproducible detection of VE-Cadherin protein expression in various experimental settings.