TTR mouse Monoclonal Antibody(4E4)

This gene encodes transthyretin, one of the three prealbumins including alpha-1-antitrypsin, transthyretin and orosomucoid. Transthyretin is a carrier protein; it transports thyroid hormones in the plasma and cerebrospinal fluid, and also transports retinol (vitamin A) in the plasma. The protein consists of a tetramer of identical subunits. More than 80 different mutations in this gene have been reported; most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart, and a small portion of the gene mutations is non-amyloidogenic. The diseases caused by mutations include amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, carpal tunnel syndrome, etc.

The TTR Mouse Monoclonal Antibody (4E4) is a highly specific and sensitive antibody that has been developed for use in various research applications. This antibody is derived from mouse hybridoma cells and has been purified using protein A affinity chromatography. It has been extensively characterized and validated for its ability to recognize and bind to the transthyretin (TTR) protein.

The TTR Mouse Monoclonal Antibody (4E4) is suitable for use in a variety of applications, including Western blotting, ELISA, immunohistochemistry, and immunofluorescence. It has been shown to exhibit high specificity and sensitivity in detecting TTR protein in various tissues and biological samples.

This antibody is supplied as a liquid formulation in phosphate-buffered saline (PBS) with 0.02% sodium azide as a preservative. It is available in various sizes to meet the needs of different research applications.

Overall, the TTR Mouse Monoclonal Antibody (4E4) is a reliable and effective tool for researchers studying the TTR protein and its role in various physiological and pathological processes. Its high specificity and sensitivity make it a valuable asset in the field of biomedical research.