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SKU:BT-MCA1190

TBP/TATA Binding Protein Monoclonal Antibody(4H2)

TBP/TATA Binding Protein Monoclonal Antibody(4H2)

Regular price $300.00 USD
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Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes TBP, the TATA-binding protein. A distinctive feature of TBP is a long string of glutamines in the N-terminus. This region of the protein modulates the DNA bin. 

Introducing the TBP/TATA Binding Protein Monoclonal Antibody (4H2), a cutting-edge scientific tool designed to facilitate accurate and efficient research in the field of molecular biology. This meticulously crafted antibody is specifically engineered to target and bind with the TBP/TATA binding protein, a crucial component in gene transcription initiation.

The TBP/TATA Binding Protein Monoclonal Antibody (4H2) boasts exceptional specificity and sensitivity, ensuring reliable and reproducible results in a wide range of experimental applications. Its high affinity for the TBP/TATA binding protein enables precise detection and quantification, enabling researchers to delve deeper into the intricate mechanisms of gene regulation.

Crafted with utmost precision and utilizing state-of-the-art technology, this monoclonal antibody guarantees exceptional performance and consistency. Its robust design allows for seamless integration into various experimental protocols, including immunoprecipitation, Western blotting, and immunofluorescence, among others.

Furthermore, the TBP/TATA Binding Protein Monoclonal Antibody (4H2) is manufactured under stringent quality control measures, ensuring batch-to-batch consistency and reliability. Each vial is meticulously tested to meet the highest standards, guaranteeing optimal performance and reproducibility.

In summary, the TBP/TATA Binding Protein Monoclonal Antibody (4H2) is an indispensable tool for researchers seeking to unravel the complexities of gene transcription initiation. With its exceptional specificity, sensitivity, and reliability, this antibody empowers scientists to advance their understanding of molecular biology and contribute to groundbreaking discoveries.

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