Stat5b Monoclonal Antibody

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL.

Introducing the STAT6 Monoclonal Antibody, a highly specific and sensitive tool for the detection and analysis of STAT6 protein expression in various biological samples. This antibody is produced using advanced monoclonal antibody technology, ensuring high purity and consistency in every batch.

The STAT6 Monoclonal Antibody is designed to recognize and bind to the STAT6 protein, a transcription factor that plays a crucial role in regulating immune responses and cell growth. Its high affinity and specificity make it an ideal tool for a wide range of applications, including western blotting, immunohistochemistry, and flow cytometry.

This antibody is validated for use in human, mouse, and rat samples, and has been extensively tested to ensure optimal performance and minimal cross-reactivity with other proteins. Its superior sensitivity and specificity make it an essential tool for researchers studying the role of STAT6 in various biological processes, including cancer, inflammation, and allergy.

In summary, the STAT6 Monoclonal Antibody is a reliable and effective tool for the detection and analysis of STAT6 protein expression in various biological samples. Its high specificity, sensitivity, and consistency make it an essential tool for researchers in the fields of immunology, oncology, and cell biology.