STAT3 Monoclonal Antibody(3F4)

The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. Mutations in this gene are associated with infantile-onset multisystem autoimmune disease and hyper

The STAT3 Monoclonal Antibody (3F4) is a highly specific and reliable tool for the detection and analysis of Signal Transducer and Activator of Transcription 3 (STAT3) protein. This antibody is produced through a rigorous and controlled process, ensuring its high quality and consistency.

The STAT3 Monoclonal Antibody (3F4) exhibits exceptional affinity and selectivity towards STAT3, making it an ideal choice for various applications, including Western blotting, immunohistochemistry, and immunofluorescence. Its superior specificity allows for accurate and precise detection of STAT3 protein in various biological samples.

This antibody is designed to provide researchers with a valuable tool for studying the role of STAT3 in cellular signaling pathways and its involvement in various diseases, such as cancer and inflammation. Its reliable performance and reproducibility make it an essential component in scientific research and drug development.

The STAT3 Monoclonal Antibody (3F4) is supplied in a convenient and ready-to-use format, ensuring ease of use and saving valuable time in the laboratory. It is recommended for use in a wide range of species, including human, mouse, and rat.

In summary, the STAT3 Monoclonal Antibody (3F4) is a highly specific and reliable tool for the detection and analysis of STAT3 protein. Its exceptional affinity and selectivity, along with its convenient format, make it an essential asset for researchers in the field of cellular signaling and disease research.