STAT3 Monoclonal Antibody(1E3)

The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. Mutations in this gene are associated with infantile-onset multisystem autoimmune disease and hyper

The STAT3 Monoclonal Antibody (1E3) is a highly specific and reliable tool for the detection and analysis of Signal Transducer and Activator of Transcription 3 (STAT3) protein. This antibody, produced through advanced monoclonal technology, exhibits exceptional affinity and selectivity towards STAT3, making it an ideal choice for various research applications.

The STAT3 Monoclonal Antibody (1E3) has been extensively validated and characterized for its superior performance in immunohistochemistry (IHC), immunofluorescence (IF), and western blotting (WB) techniques. Its exceptional sensitivity and specificity enable accurate and precise detection of STAT3 protein expression in various biological samples.

This antibody is manufactured under stringent quality control measures to ensure batch-to-batch consistency and reproducibility. It is supplied as a ready-to-use solution, eliminating the need for time-consuming and error-prone antibody preparation steps. The STAT3 Monoclonal Antibody (1E3) is compatible with a wide range of experimental conditions and can be used in diverse research areas, including cancer biology, immunology, and signal transduction pathways.

With its exceptional performance and reliability, the STAT3 Monoclonal Antibody (1E3) is an indispensable tool for scientists and researchers seeking to unravel the intricate mechanisms of STAT3 signaling and its implications in various physiological and pathological processes.