STAT1 mouse Monoclonal Antibody(8H11)

The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described.

The STAT1 Mouse Monoclonal Antibody (8H11) is a highly specific and reliable tool for the detection and analysis of STAT1 protein expression in various biological samples. This antibody is produced using advanced monoclonal antibody technology, ensuring high affinity and specificity towards STAT1.

The STAT1 protein plays a crucial role in the regulation of cellular responses to various cytokines and growth factors. It is involved in the activation of the JAK-STAT signaling pathway, which is essential for the modulation of immune responses, cell proliferation, and differentiation. The STAT1 Mouse Monoclonal Antibody (8H11) enables researchers to investigate the function and regulation of STAT1 in diverse cellular processes.

This antibody has been extensively validated for its performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits excellent sensitivity and specificity, allowing for accurate and reliable detection of STAT1 protein expression in different experimental settings.

The STAT1 Mouse Monoclonal Antibody (8H11) is supplied as a purified and concentrated solution, ensuring optimal performance and ease of use. It is suitable for both research and diagnostic purposes, providing valuable insights into the role of STAT1 in various physiological and pathological conditions.

With its exceptional quality and performance, the STAT1 Mouse Monoclonal Antibody (8H11) is an indispensable tool for scientists and researchers working in the fields of immunology, cell biology, and molecular biology.